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  • br Essery R Geraghty AW Kirby S Yardley

    2020-08-07


    [25] Essery R, Geraghty AW, Kirby S, Yardley L. Predictors of adherence to home-based physical therapies: a systematic review. Disabil Rehabil Mar 2017;39(6):519–34. [26] Lambert SD, Duncan LR, Kapellas S, et al. A descriptive systematic review of physical activity interventions for caregivers: effects on caregivers' and care recipients' psy-chosocial outcomes, physical activity levels, and physical health. Ann Behav Med Dec 2016;50(6):907–19.
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    [28] Musich S, Wang SS, Kraemer S, Hawkins K, Wicker E. Caregivers for older adults: prevalence, characteristics, and health care utilization and expenditures. Geriatr Nurs Jan - Feb 2017;38(1):9–16.
    [29] Pergolotti M, Williams GR, Campbell C, Munoz LA, Muss HB. Occupational therapy for adults with cancer: why it matters. Oncologist Mar 2016;21(3):314–9. [30] Ormel HL, van der Schoot GGF, Westerink NL, Sluiter WJ, Gietema JA, Walenkamp AME. Self-monitoring physical activity with a smartphone application in cancer pa-tients: a randomized feasibility study (SMART-trial). Support Care Cancer Nov 2018; 26(11):3915–23.
    Platinum Priority – Prostate Cancer
    Editorial by Rebecca E. Graff, Linda Kachuri and John S. Witte on pp. 408–409 of this issue
    Baseline Prostate-specific BYL-719 Level in Midlife and Aggressive Prostate Cancer in Black Men
    Mark A. Preston a,y,*, Travis Gerke b,c,y, Sigrid V. Carlsson d,e,g, Lisa Signorello b,f, Daniel D. Sjoberg g, Sarah C. Markt b, Adam S. Kibel a, Quoc-Dien Trinh a, Mark Steinwandel i, William Blot i,j, Andrew J. Vickers g, Hans Lilja d,k,l,m, Lorelei A. Mucci b,z, Kathryn M. Wilson b,h,z,*
    a Division of Urology, Brigham and Women's Hospital, Boston, MA, USA; b Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA; c Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, USA; d Department of Surgery (Urology Service), Memorial Sloan Kettering Cancer Center, New York, NY, USA; e Department of Urology, Institute of Clinical Sciences, Sahlgrenska Academy at University of Göteborg, Göteborg, Sweden; f Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA; g Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA; h Channing Division of Network Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, MA, USA;
    i Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA; j Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA; k Departments of Laboratory Medicine and Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; l Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; m Department of Translational Medicine, Lund University, Malmö, Sweden
    Article info
    Article history:
    Associate Editor:
    Matthew Cooperberg
    Keywords:
    African-American
    Baseline
    Prostate cancer
    Prostate-specific antigen
    Screening
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    Abstract
    Background: Prostate-specific antigen (PSA) measurement in midlife predicts long-term prostate cancer (PCa) mortality among white men. Objective: To determine whether baseline PSA level during midlife predicts risk of aggressive PCa in black men. Design, setting, and participants: Nested case-control study among black men in the Southern Community Cohort Study recruited between 2002 and 2009. A prospective cohort in the southeastern USA with recruitment from community health centers. A total of 197 incident PCa patients aged 40–64 yr at study entry and 569 controls matched on age, date of blood draw, and site of enrollment. Total PSA was measured in blood collected and stored at enrollment.
    Outcome measurements and statistical analysis: Total and aggressive PCa (91 aggres-sive: Gleason 7, American Joint Committee on Cancer stage III/IV, or PCa-specific death). Exact conditional logistic regression estimated odds ratios (ORs) with 95% confidence intervals (CIs) for PCa by category of baseline PSA.
    y These authors contributed equally as first authors. z These authors contributed equally as senior authors.
    E-mail addresses: [email protected] (M.A. Preston), [email protected] (K.M. Wilson).
    Conclusions: PSA levels in midlife strongly predicted total and aggressive PCa among black men. PSA levels among controls were similar to those among white controls in prior studies.